AI Agents
Agon
Autonomous research loops, from topic to experiments.
★ 54 starsMIT
View guide →OpenScience — the open-source AI workbench for scientific research: give it a goal, it reads the literature, runs the experiments and writes up the findings
OpenScience is an open-source ai agents project by synthetic-sciences (synthetic-sciences/openscience on GitHub). It has 4,004 GitHub stars and 526 forks, is released under the Apache-2.0 license, and was last updated on GitHub on 13 October 2026.
Install globally from npm, or run the desktop app or browser workspace if you prefer a GUI.
Describe the research task in plain language — a claim to reproduce, a dataset to clean, a parameter sweep to run.
Follow the visible trace of searches, code and file changes, then read the written-up results and check them like any lab notebook.
A turn reads as what happened — reasoning, searches, runs and writes — so nothing happens that you cannot inspect afterwards.
Shell access, Python and R kernels, notebooks, and a file system with explicit read and write grants.
Desktop app, browser workspace or terminal command — on your machine, against your files.
The desktop app updates itself; the CLI upgrades with a single openscience upgrade command.
The CLI package is published as @synsci/openscience.
npm install -g @synsci/opensciencenpx launches the workbench directly.
npx synsciKeep an npm installation current with the built-in upgrade command.
openscience upgradesynthetic-sciences; the project site is openscience.sh.
Yes, Apache-2.0 licensed and published on npm.
The workbench is free; the underlying model usage follows whichever provider account or key you configure.
Hosted deep-research tools return an answer; OpenScience returns an inspectable record — the searches, code and files behind the answer — and runs locally against your own files.
Run npm install -g @synsci/openscience (or npx synsci), open the workbench, and describe your research goal in plain language.
Autonomous research loops, from topic to experiments.
An autonomous research agent that plans, searches and writes cited reports from any data source
Devika - the open-source agentic software engineer that plans, browses and writes code
A lean, HuggingFace-native RL framework for agentic research.
Deep research that stays on your machine — local or cloud LLMs, 10+ search engines, encrypted and private.
An embeddable, portable, branchable microVM that runs AI agents safely on your own machine.
The most-starred other AI Agents projects in the LibreAI catalogue — the realistic shortlist if OpenScience is not the right fit.
A personal AI that really does things — on any OS, with your data staying yours.
An agentic skills framework & software development methodology that works.
Agent harness optimization system with skills, memory and security for Claude Code, Codex and more
The agent that grows with you — a Python framework for adaptive AI agents.
DeepSeek's plugin-based agent harness where everything is a plugin.
Free and open — grab the source, star the repo, and start creating.